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足月新生儿眼轴长度测量及分析

 

目的通过测量足月新生儿眼轴长度(AL),探讨正常新生儿AL的正常范围、特点及AL与胎龄、出生体质量等的关系。方法横断面研究。选取年7月至年1月出生的足月新生儿例,应用A超测量出生1~3d新生儿双眼的AL。观察不同性别、胎龄、出生体质量、分娩方式足月新生儿的AL分布情况。采用t检验、单因素方差分析、Pearson相关分析及多元线性回归进行数据处理。结果例(眼)足月新生儿的右眼和左眼AL分别为(16.54±0.59)mm、(16.54±0.56)mm,差异无统计学意义。以左右眼AL均值作为该新生儿的AL,足月新生儿AL平均值为(16.54±0.57)mm,95%CI为16.50~16.58mm,其中男性新生儿AL为(16.55±0.57)mm,女性新生儿AL为(16.53±0.57)mm,差异无统计学意义。胎龄为37、38、39、40、41周组新生儿(各胎龄组分别为例)的平均AL分别为(16.14±0.43)mm、(16.50±0.32)mm、(16.51±0.40)mm、(16.70±0.69)mm、(16.86±0.67)mm。出生体质量2.5~、3.0~、3.5~4.0kg组新生儿AL分别为(16.34±0.52)mm、(16.52±0.51)mm、(16.73±0.61)mm。AL与胎龄、出生体质量均呈正相关(r=0.、0.,P0.01)。与性别、分娩方式无相关性。将胎龄、出生体质量等因素纳入多元回归模型,得出回归方程:AL=10.+0.×胎龄。结论正常足月新生儿平均AL为(16.54±0.57)mm。AL随着胎龄、出生体质量的增加而延长,而与性别、分娩方式无关。

眼轴长度;婴儿,新生;出生体重;足月分娩

Measurementandanalysisoftheaxiallengthoffull-termnewborns

MaoJianbo*,LiLihong,HongMingsheng,LiNa,ChuMengqi,ShenLijun.*EyeHospitalofWenzhouMedicalUniversity,Wenzhou,China

Correspondingauthor:ShenLijun,Email:slj

mail.eye.ac.cn

ObjectiveTomeasurethefull-termnewbornsaxiallength(AL),andtostudytheassociationswithgestationalage,birthweight,deliverymode,gender.MethodsThiswasacross-sectionalstudy.Asubsetoffull-termneonates(eyes)wereincluded.Theageofneonatesrangedfrom1to3days.ALwasmeasuredquantitativelybyAultrasound.Associationswithatenatalfactorswerealsostudied,whichincludegender,gestationalage,birthweight,anddeliverymode.Datawereanalyzedusingttest,one-wayANOVA,Pearsoncorrectionandmultivariablelinearregressionanalysis.ResultsNosignificantdifferencebetweentherighteyes16.54±0.59mmandthelefteyes16.54±0.56mmALwasfound.ThemeanvalueofleftandrighteyeALwasdefinedastheneonatalAL.MeanlongitudinalALwas16.54±0.57mm,95%CI16.50~16.58mm.Thereweremaleneonates(50.1%)femaleneonates(49.9%),whoseALwere16.55±0.57mmand16.53±0.57mm.ThemeanALofdifferentgestationalagefrom37weeksto41weekswere16.14±0.43mm,16.50±0.32mm,16.51±0.40mm,16.70±0.69mm,16.86±0.67mm.BothbirthweightandgestationalagewerepositivelycorrelatedwithAL(r=0.,0.,P0.01).ThemeanALofdifferentbirthweightfrom2.5~,3.0~,3.5~4.0kgwere16.34±0.52mm,16.52±0.51mm,16.73±0.61mm.ALhadnocorrelationwithgender,deliverymode.Multiplelinearregressionanalysisshowedtheregressionequation:AL=10.+0.×gestationalage.ConclusionThefull-termnewbornALwas16.54±0.57mm.TherewasnosignificantdifferencebetweentherighteyesandthelefteyesAL.GestationalageandbirthweightwerepositivelycorrelatedwithAL.

Axiallength;Infant,newborn;Birthweight;Termdelivery

DOI:10.0/cma.j.issn.-X..09.

作者单位:温州医医院(毛剑波、洪明胜、褚梦琪、沈丽君);云南省昆明市妇幼保健院(李丽红、李娜)

通信作者:沈丽君,Email:slj

mail.eye.ac.cn

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